SKU: DULANE30 Category: Tags: ,


What is Dulane 30mg?

Dulane 30 MG Capsule is a drug used to treat depression. It’s used to help nervousness, sadness, and other mood problems. People with fibromyalgia and diabetic neuropathic pain (nerve damage from high blood sugar) also use it to treat their pain.

What is the use of Dulane 30mg?

Dulane 30mg (Duloxetine) is used for a variety of medical conditions, primarily in the realm of mental health and chronic pain management. Here are its primary uses:

1. Major Depressive Disorder (MDD)

Dulane is commonly prescribed to treat major depressive disorder. It helps alleviate symptoms such as persistent sadness, loss of interest in activities, changes in appetite or weight, insomnia or excessive sleeping, fatigue, feelings of worthlessness, and difficulty concentrating.

2. Generalized Anxiety Disorder (GAD)

It is also effective in treating generalized anxiety disorder, characterized by excessive and uncontrollable worry about various aspects of daily life. Symptoms include stiff muscles, restlessness, fatigue, difficulty concentrating, irritability, and inconsistent sleep patterns.

3. Social Anxiety Disorder (SAD):

Social Anxiety Disorder (SAD), also known as social phobia, is a common mental health condition characterized by intense fear or anxiety about social situations. Individuals with SAD may experience significant distress and avoidance behaviors in social settings, fearing negative evaluation, embarrassment, or humiliation.

Mechanism of Action

Dulane, also known as duloxetine, is an SNRI, or serotonin-norepinephrine reuptake inhibitor. Dulane’s active component, duloxetine, is an SNRI (serotonin-norepinephrine reuptake inhibitor). It works by modulating the brain’s neurotransmitters, which are molecules that carry messages from one nerve cell to another.

How does Dulane 30mg Works?

  • Neurotransmitters Involved: Serotonin (5-HT) and norepinephrine (NE) are key neurotransmitters involved in regulating mood, anxiety, and pain perception.
  • Reuptake Inhibition: Duloxetine works by inhibiting the reuptake of serotonin and norepinephrine into neurons. This increases the levels of these neurotransmitters in the synaptic cleft (the space between neurons), enhancing their positive effects on mood and pain.
  • Depression: In major depressive disorder, an imbalance of serotonin and norepinephrine is often observed. By increasing the levels of these neurotransmitters, Duloxetine helps alleviate depressive symptoms such as persistent sadness, loss of interest in activities, and cognitive dysfunction.
  • Anxiety: For generalized anxiety disorder, the increased availability of serotonin and norepinephrine helps reduce excessive worry, restlessness, and physical symptoms of anxiety.


Some people may begin by taking 30 mg once a day for one week and then be given 60 mg once a day. Your doctor may increase your dosage if it’s required.

The daily amount should not be more than 120 mg, though. Older people: Take 30 mg once a day for two weeks, then up the amount to 60 mg once a day.

Side Effects

Common side effects of Dulane (Duloxetine) may include:

  • Nausea
  • Dry mouth
  • Drowsiness
  • Fatigue
  • Constipation
  • Loss of appetite
  • Increased sweating
  • Sleepiness
  • Dizziness

Though they are less frequent, serious adverse effects might include:

  • Liver damage
  • Serotonin syndrome, a disorder caused by an excess of serotonin that may be fatal.


  • Liver and Kidney Function: Duloxetine is metabolized in the liver and excreted through the kidneys. This medicine should be used cautiously by patients who have impaired liver or renal function.
  • Interaction with Other Medications: Duloxetine can interact with other medications, so it’s essential to inform the healthcare provider of all medications currently being taken.

Safety Warnings for Dulane 30mg (Duloxetine)

Dulane 30mg, containing Duloxetine, has several safety warnings that patients and healthcare providers should be aware of to ensure its safe and effective use.

1. Serotonin Syndrome

  • Risk: This potentially life-threatening condition can occur when Duloxetine is taken alone or in combination with other serotonergic drugs (e.g., SSRIs, SNRIs, triptans, tramadol, etc.).
  • Symptoms: Symptoms include agitation, hallucinations, rapid heart rate, high blood pressure, muscle rigidity, and incoordination.
  • Action: Seek immediate medical attention if these symptoms occur.

2. Liver Damage

  • Risk: Duloxetine can cause liver damage, which may be severe.
  • Symptoms: Signs include dark urine, jaundice (yellowing of the skin or eyes), severe abdominal pain, and persistent nausea/vomiting.
  • Monitoring: It may be required to do routine liver function testing.

3. Orthostatic Hypotension and Syncope

  • Risk: Duloxetine can cause a sudden drop in blood pressure upon standing, leading to dizziness or fainting.
  • Precautions: Patients should be advised to rise slowly from a sitting or lying position.


Q: Dulane 30mg, How long does it take to work?

Within one to two weeks of taking the medicine, patients may start to feel some change in their symptoms. That being said, it might take up to 4 to 6 weeks to feel the full healing benefits. Within one to two weeks, some people may start to feel less pain. It may take a few weeks, and often up to four weeks, for the full benefits to show.

Q: If I feel better, can I stop taking Dulane 30 mg?

No, even if you feel better, you shouldn’t stop taking Dulane (duloxetine) 30 mg all of a sudden. If you stop taking duloxetine all of a sudden, you might experience withdrawal signs and your condition might get worse again. Before making any changes to your drug schedule, you should always talk to your doctor or nurse. They can help you figure out how to stop taking the medicine safely if it’s time. If you and your doctor decide it’s time to stop taking Dulane, your doctor will probably suggest that you stop taking it slowly instead of all at once. This helps to lessen the effects of addiction.

Q: What do you feel when you first take duloxetine?

Some common side effects are feeling sick, having a dry mouth, and falling asleep. Some people who take it say they feel “more grounded” and in charge of their feelings. Others say the medicine made them feel less emotional than they thought it would.

Q: Say you take 30 mg of duloxetine. What does it heal?

A drug called duloxetine is used to help nervousness and sadness. It’s also used to treat pain caused by diabetic peripheral neuropathy, which is nerve damage caused by diabetes. People with fibromyalgia (pain and stiffness in the muscles) and people with chronic (long-lasting) pain in their bones and muscles can also take duloxetine.


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